Letrozole is an anti-estrogen of the Aromatase Inhibitor (AI) family and is one of the most potent and powerfully effective of all AI’s. In fact, its potency is sometimes too much for some to handle when used for off label use. Letrozole first gained U.S. FDA approval in 1997 and would hit the market under the brand name Femara through Novartis. Although Femara is the dominating trade name of the AI, unlike most AI’s it is the only one generally known by its chemical name Letrozole far more commonly than its dominating brand name.
The recommended dosage of Femarais one tablet a day (2.5 milligrams), which can lower estrogen levels by 78%, as shown in clinical trials. However, anecdotal feedback reports that it can still be effective even taken at a much lower dose – a 0.5 milligram a day can elicit ideal estrogen inhibition.
How to use:
For the anabolic steroid user, Letrozole doses will normally be much lower. Even with the use of anabolic steroids, a 2.5mg dosing will normally be too high and could potentially drain the individual of energy; in fact, it’s almost guaranteed. If symptoms begin to show 7-14 days at a dose of 2.5mg per day can reverse the symptoms. Once symptoms begin to fade away the individual should be able to tapper down to a more manageable dose and maintain it for the remainder of the cycle.