Trenbolone Enanthate is a19-nor steroid, very similar to Nandrolone. The primary difference between Trenbolone is that there is a double carbon bond present at the 9 and 11 position on the steran nucleus. Trenbolone can not aromatize to estrogen nor be 5a-reduced. It bonds very tightly to the Androgen Receptor, and for this reason it is thought that much of its fat-burning and muscle building abilities are receptor mediated.Trenbolone Enanthate use produces an impressive amount of new muscle fiber, with minimal water retention (1) This may be done partly through an increase in IGF-1 within muscle tissue (2), and increased sensitivity of muscle satellite to IGF-1 and other growth factors(3) and an increase in the amount of DNA per muscle cell. It has a very strong binding affinity to the androgen receptor (A.R), binding much more strongly than testosterone (4) as well as nandrolone. Trenbolone increases both protein synthesis as well as nitrogen retention in muscle tissue (5). Trenbolone can also bind with the (anti-anabolic) glucocorticoid receptor (6-7), thus aiding the muscle building process. Finally, it also has the ability to improve nutrient efficiency and mineral absorption in animals given the drug (8-9).
As a long ester based Tren, Trenbolone-Enanthate does not need to be injected very frequently, in-fact most will find 2 injections per week or simply a schedule of one every 4 days to be sufficient. You will also find this compound on a per milligram basis to be a little weaker than Trenbolone-Acetate, meaning to receive the same dosing with Tren-E as it is most commonly known the individual would need a little more on a weekly basis to receive the same amount as if the Acetate version were being used. The reason for this is simple; when we take 100mg of both forms a larger amount of the Tren-E form is ester, as larger esters take up more mass in a compound than smaller ones.
How to use:
Regardless of purpose, be it bulking or cutting most will find Trenbolone-Enanthate to be very effective in the 300mg-500mg per week range with 400mg per week generally being a very solid dose. Yes, you can use more but most will find doses that get much past 500mg per week to be a little less side-effect friendly, especially if they enter the 600mg per week range and almost assuredly if they surpass 700mg per week. Regardless of dosing most will find 8 weeks to be decently effective with 12 weeks of use generally being as far as you want to go. If your cycle is extended past 12 weeks it’s normally best to substitute another anabolic hormone in Tren’s place in-order to keep progress alive; yes, our body will adapt.