Tramadol (also known as Ultram, Ralivia or Tramal) is a synthetic opioid substance of the cyclohexanol class that is structurally related to codeine and morphine. It acts as a weak μ-opioid receptor agonist and a reuptake inhibitor of norepinephrine and serotonin. It is commonly prescribed to treat moderate to moderately severe pain.
Subjective effects are largely consistent with that of traditional opioids and include sedation, pain relief, anxiety suppression, muscle relaxation, and euphoria. Tramadol is also known to produce mild to moderate entactogenic effects like increased music appreciation and empathy, affection, and sociability enhancement, which is thought to be due to its serotonergic effects.