Applying isotretinoin to the areas of your skin with acne will help to unblock pores and treat blackheads or whiteheads. It also has some effect on reducing inflammation. If your spots are inflamed, you may be prescribed a brand called Isotrexin® as this gel also contains an antibacterial agent called erythromycin.
Apply isotretinoin gel exactly as your doctor tells you to. It is best if you wash and gently dry the affected areas of your skin before you apply isotretinoin. A general point is that you should apply it to all of the area where your spots occur and not just to each spot. It is usual to apply it once or twice a day at first, although your doctor may suggest you use it less than this once your skin has improved. You only need to apply a thin layer of gel. Remember to wash your hands after you have finished applying the gel.
If you have recently been using a preparation for your acne that causes your skin to peel, allow your skin to recover for a few days before you start using isotretinoin gel.
Do not use the gel on any areas of your skin which are sunburnt or sore. Also, try to avoid getting it on the sensitive areas of your skin in or around your nostrils, your eyes and your mouth. Try not to let it build up in the folds or creases of your skin.