Description
Cyproterone belongs to a group of medications known as steroidal antiandrogens. It is used to treat advanced prostate cancer. Antiandrogens such as cyproterone block the effect of the hormone called testosterone. This causes a reduction in the production of testosterone in the testicles, which prostate cancer cells require for growth.
Cyproterone is available as an oral (by mouth) tablet and as a long-acting injectable. The recommended dose for cyproterone tablets is 200 mg to 300 mg (4 to 6 tablets) daily, divided into 2 to 3 doses and taken after meals. For men who have had an orchiectomy (removal of testicles), a lower dose of 100 mg to 200 mg daily in divided doses is recommended.
The recommended dose for the long-acting form of cyproterone (Androcur® Depot) is 300 mg injected into a muscle once a week. For men who have had an orchiectomy, the recommended dose is 300 mg injected every 2 weeks.
