Ace-031, also known as ACVR2B, is a soluble form of activin type IIB receptor, which is an inhibitor of myostatin and other naturally occurring proteins that limit muscle growth. This compound was genetically developed to bind to myostatin before it can attach to its receptor and halt muscle growth.
Scientists and researchers study the ACVR2B bio-peptide for its potential to treat a variety of health conditions and diseases ranging from cancer to cardiovascular abnormalities, to metabolic diseases, to muscular damage and neuromuscular disease. Studies show that ACVR2B stops cells from signaling processes by blocking the ActRIIB receptor which increases muscle power. ActRIIB is basically the switch that turns muscle growth on and off. Using recombinant technology, proteins can be fused to eliminate myostatin, which allows more muscle growth and strength such as was shown in the studies of mutant mice that were missing myostatin.